Top Ingredients in Hemo Flow That Support Healthy Blood Flow

Not all blood flow supplements are created equal. Walk into any supplement store and you'll find shelves of pre-workouts and "pump" formulas making big claims — but most rely on a single mechanism: nitric oxide production. While NO support is valuable, true circulatory health is far more complex.

Leviathan Nutrition Hemo Flow V3, available at NF Supps, takes a different approach. Instead of chasing one pathway, it stacks six clinically inspired ingredients that work together to address blood pressure, blood viscosity, oxygen-carrying capacity, and nutrient absorption. Here's a deep dive into each one and the science behind why it's in the formula.

1. VasoDrive-AP™ — 508mg

What It Is

VasoDrive-AP™ is a patented ingredient containing two bioactive tripeptides — Isoleucine-Proline-Proline (IPP) and Leucine-Lysine-Proline (LKP) — derived from casein protein through enzymatic hydrolysis.

How It Works

These tripeptides function as ACE inhibitors — they block angiotensin-converting enzyme (ACE), which is responsible for producing angiotensin II, a potent vasoconstrictor. By inhibiting ACE, VasoDrive-AP™ helps blood vessels relax and widen, supporting healthy blood pressure and improving overall blood flow. This is the same mechanism targeted by a class of widely prescribed cardiovascular medications — but delivered through a natural, food-derived peptide.

Why It Matters

Chronically elevated blood pressure is one of the most common and underappreciated threats to long-term cardiovascular health. VasoDrive-AP™ provides a natural, evidence-backed way to support healthy pressure levels without stimulants or harsh compounds.

2. Nattokinase — 10,000 FU / 500mg

What It Is

Nattokinase is a serine protease enzyme extracted from natto — a traditional Japanese food made from fermented soybeans. It has been studied extensively for its cardiovascular benefits and is measured in Fibrinolytic Units (FU), reflecting its enzymatic activity.

How It Works

Nattokinase is a fibrinolytic enzyme, meaning it helps break down fibrin — a protein involved in blood clot formation and a key contributor to blood viscosity. By supporting healthy fibrin levels, nattokinase helps keep blood flowing freely and efficiently through vessels. Research shows it supports healthy blood viscosity and circulation without the adverse effects associated with pharmaceutical anticoagulants.

Why It Matters

Blood viscosity is a critical but often overlooked factor in circulatory health. Thicker blood is harder to pump, delivers oxygen and nutrients more slowly, and places greater strain on the cardiovascular system. Nattokinase addresses this directly at a meaningful clinical dose.

3. Lavitol® DHQ (Dihydroquercetin) — 60mg

What It Is

Lavitol® is a premium, standardized form of dihydroquercetin (DHQ) — a flavonoid antioxidant derived from Siberian larch wood. It is one of the most potent natural antioxidants known, with significantly higher bioavailability than standard quercetin.

How It Works

DHQ supports blood flow through two distinct mechanisms. First, when combined with Vitamin C, it has been clinically shown to reduce blood viscosity by 15–17% — a meaningful reduction that improves the ease with which blood moves through vessels. Second, DHQ acts as an iron chelator, helping to regulate excess iron in the blood. Elevated iron levels can increase hematocrit (the ratio of red blood cells to plasma), thickening the blood and reducing circulatory efficiency. By modulating iron, DHQ helps maintain hematocrit in a healthy range, supporting optimal oxygen-carrying capacity.

Why It Matters

DHQ is one of the most versatile ingredients in the formula — simultaneously reducing viscosity, protecting vessels from oxidative damage, and supporting the balance of red blood cell concentration in the bloodstream.

4. Vitamin C — 120mg

What It Is

Vitamin C (ascorbic acid) is an essential water-soluble vitamin and one of the most well-researched antioxidants in human health.

How It Works

In Hemo Flow V3, Vitamin C plays a dual role. It works synergistically with DHQ to amplify the blood viscosity reduction effect — the two compounds together produce a significantly greater impact than either alone. Vitamin C also supports endothelial function — the health of the cells lining blood vessel walls — and acts as a potent antioxidant that protects vascular tissue from oxidative stress generated during intense exercise and normal metabolic activity.

Why It Matters

Oxidative stress is a primary driver of vascular aging and endothelial dysfunction. By pairing Vitamin C with DHQ, Hemo Flow V3 creates a synergistic antioxidant and viscosity-reducing effect that neither ingredient achieves alone.

5. Naringin (Grapefruit Extract) — 200mg

What It Is

Naringin is a flavonoid glycoside found primarily in grapefruit and other citrus fruits. It is well-studied for its cardiovascular and metabolic effects.

How It Works

Naringin supports vascular health and healthy lipid levels through its anti-inflammatory and antioxidant properties. It also plays a key role in enhancing the bioavailability of co-administered nutrients by inhibiting certain metabolic enzymes that would otherwise break down active compounds before they reach systemic circulation. Think of it as the formula's delivery amplifier — helping every other ingredient work more effectively.

Why It Matters

Even the most clinically dosed formula is only as effective as what actually gets absorbed. Naringin ensures the rest of the Hemo Flow V3 stack reaches its full potential in the body.

6. BioPerine® — 10mg

What It Is

BioPerine® is a patented black pepper extract standardized to 95% piperine — the compound responsible for black pepper's bioavailability-enhancing properties.

How It Works

BioPerine® works by inhibiting certain digestive enzymes and intestinal transporters that would otherwise limit absorption of polyphenols and other nutrients. It has been specifically shown to maximize the bioavailability of dihydroquercetin and similar flavonoids, ensuring that the DHQ in Hemo Flow V3 is absorbed efficiently rather than passing through unmetabolized.

Why It Matters

Premium ingredients at clinical doses mean nothing if they aren't absorbed. BioPerine® is the final piece of the formula — ensuring the entire stack delivers on its promise.

Why the Stack Matters More Than Any Single Ingredient

What makes Hemo Flow V3 stand out isn't any one ingredient — it's the way these six compounds work together. VasoDrive-AP™ relaxes vessels. Nattokinase thins the blood. DHQ and Vitamin C reduce viscosity and protect vascular tissue. Naringin and BioPerine® ensure everything gets absorbed. The result is a formula that addresses circulatory health from every meaningful angle.

Each bottle contains 30 servings of vegan-friendly capsules, made in the USA and third-party tested for purity and potency. Available now at NF Supps — Cleveland's home for premium, science-backed supplements.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.