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Supplement Ingredients - Citrulline Malate

January 06, 2018 3 min read

Citrulline Malate is commonly found in pre-workout and BCAA products. The ingredient is mainly used for increasing the "pump" or blood flow during exercise. Below you will find info on how it works, what it does, what to expect, dosages, and what products it can be found in.

I am by no means a chemist or certified supplement expert, but I have gathered info from various sources and translated most of it in my own words.

What is Citrulline Malate & How does it work?

Citrulline Malate is the supplemental form of the non-essential amino acid citrulline. This supplemental form is the product of bonding a salt compound, malic acid, to the amino acid citrulline

But don’t let the words “non-essential” fool you. Non-essential doesn’t mean this amino acid isn’t important, it simply means that your body creates it naturally. Citrulline Malate’s benefits directly relate to its effects on arginine and nitric oxide, which helps improve blood flow throughout the body.

The body does produce Citrulline, but not in quantities that will produce any performance benefits. Research shows that supplementing your workouts and training with this supplemental citrulline malate form can improve your performance and recovery.

I hope this info helps and if interested in checking out some products with doses of Citrulline Malate greater than 3g, here is the LINK.

Increasing Nitric Oxide

Citrulline Malate in fact raises nitric oxide levels.

Studies have shown that supplementation of Citrulline raises Arginine levels more effectively than taking the same dose of actual Arginine.

Citrulline malate helps increase blood flow because your body converts it into L-arginine and then into nitric oxide. Nitric oxide isone of the chemicals that causes vasodilation, or widening of the blood vessels, when you exercise. When your blood vessels widen, they’re able to transport blood through your body more efficiently. Improved blood flow during exercise helps tremendously because this means more oxygen and nutrient transport to the working muscles.

Lowering Lactic Acid

Citrulline is an intermediate in the Urea Cycle. The Urea Cycle is a system in the liver of carrier molecules and enzymes that convert nitrogenous wastes into urea and eliminates them from the body.

The production and removal of urea is essential for the elimination of ammonia and toxic nitrogen metabolites. Ammonia is extremely toxic to all cells and the build up of ammonia can lead to extreme fatigue. It also reduces glycogen formation, and inhibits the energy cycle.

Any exercise produces these toxins and there's really no stopping it. The more ammonia in your blood, results in decreased performance.

Research suggests that Citrulline Malate may help to eliminate the burn associated with lactic acid build up as well as reduce the negative effects of ammonia and bacterial endo toxins on performance. The metabolic actions of Citrulline Malate clearly explain the anti-fatigue properties in anyone performing any type of exercise, and shows great promise to its uses as a performance enhancer.

Clinical Dosages

Most studies indicate that an optimum dosage of 6-8g was sufficient to cause an ergogenic effect during resistance training, however it is possible that performance benefits could be seen with dosages from 3g.

Side Effects

Most commonly the side effect people supplementing with citrulline may encounter is gastrointestinal distress, but this can be avoided by taking citrulline on an empty stomach.


In conclusion, Citrulline Malate is a great ingredient to supplement for increased performance for any type of exercise. It is a safe ingredient that virtually anyone can take and can be used during anytime of the day, or night.

I hope this info helps and if interested in checking out some products with doses of Citrulline Malate greater than 3g, here is the LINK.

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NutriFit is a locally and privately owned nutritional supplement retail company specializing in high-quality products, competitive pricing, nutritional information and excellent customer service.

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